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KMID : 0882420110800010082
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Korean Journal of Medicine
2011 Volume.80 No. 1 p.82 ~ p.86
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A Case of Undifferentiated Carcinoma with Osteoclast-Like Giant Cells in the Pancreas
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Yang Suh-Yoon
Chang Se-Kyung
Park Eon-Sub
Do Jae-Hyuk
Oh In-Soo
Lee Hyng-Woong
Choi Chang-Hwan
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Abstract
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Undifferentiated carcinomas with osteoclast-like giant cells are rare pancreatic and periampullary neoplasms that mimic giant cell tumors of bone morphologically. Recently, we experienced an osteoclast-like giant cell tumor arising in the tail of the pancreas. A 76-year-old male was admitted with epigastric discomfort and indigestion. Abdominal computed tomography (CT) and abdominal magnetic resonance imaging (MRI) showed a 3×3-cm mass containing necrotic and hemorrhagic areas in the tail of the pancreas. A distal pancreatectomy and splenectomy were performed. Histological examination showed tumor cell components consisting of mononuclear pleomorphic cells admixed with osteoclastic giant cells. The final diagnosis was undifferentiated carcinoma with osteoclast-like giant cells with ductal adenocarcinoma in the pancreas.
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KEYWORD
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Pancreas, Osteoclast-like giant cells, Undifferentiated carcinoma
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